Methoxypropiophenone, CAS No. 121-97-1

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121-97-1

Catalog No. EBD23199

CAS 121-97-1

Name Methoxypropiophenone

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Basic Information

Synonyms: methoxypropiophenone 4'-methoxypropiophenone 1-(4-methoxyphenyl)-1-propanon 1-(4-methoxy-phenyl)-propan-1-one Ethyl4-methoxyphenylketone Propiophenone,4'-methoxy- P-METHOXYPROPIOPHENONE 1-(4-METHOXYPHENYL)-1-PROPANONE 4-PROPIONYLANISOLE 1-propanone,1-(4-methoxyphenyl) 4'-METHOXYPROPIOPHENONE,99+% 4'-Methoxypropiophenone99% 1-(2-methoxyphenyl)propan-1-one 4-Methoxypropiophenone

Molecular Formula: C10H12O2

Molecular Weight: 164.2

MDL Number: MFCD00009310

Categories: Synthetic Chemistry > Organic Building Blocks > Aldehydes and Ketones Medicinal Chemistry > Pharmaceutical Intermediates > Other Pharmaceutical Intermediates

Product Description:

4'-Methoxypropiophenone is an organic compound featuring a propiophenone core structure substituted with a methoxy group at the para position of the phenyl ring. It is a pale yellow to colorless liquid or low-melting solid at room temperature. This compound serves as a versatile aromatic ketone building block in organic synthesis. Its primary application is as a key synthetic intermediate in the pharmaceutical industry. It is notably used in the synthesis of various active pharmaceutical ingredients (APIs) and fine chemicals. For instance, it is a crucial precursor in the synthesis of certain adrenergic agents and other biologically active molecules. The carbonyl and methoxy groups provide reactive sites for further chemical transformations, such as reductions, alkylations, and cyclizations. While not a final drug substance itself, its role is firmly established in the production chain of specific medicinal compounds, categorizing it as a pharmaceutical intermediate. It is also utilized in research laboratories for method development and the construction of more complex molecular architectures.

Physical Properties

Melting Point: 27-29 °C(lit.)

Boiling Point: 273-275 °C(lit.)

Flash Point: 61 °C

Density: 0.937 g/mL at 25 °C(lit.)

Refractivity: n20/D 1.5465(lit.)

Analytical Data

Appearance: Clear colourless to amber liquid