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    1198090-73-1

    Catalog No. EBD4050425

    CAS 1198090-73-1

    Name 1-(4-(2-hydroxy-3-(2-(2-methoxyphenoxy)ethylamino)propoxy)-9H-carbazol-9-yl)-3-(2-(2-methoxyphenoxy)ethylamino)propan-2-ol

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    Basic Information

    Synonyms: Carvedilol EP IMpurity E

    Molecular Formula: C36H43N3O7

    Molecular Weight: 629.753

    Categories: Medicinal Chemistry > APIs and Their Salts > Cardiovascular Drugs Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

    Product Description:
    1-(4-(2-hydroxy-3-(2-(2-methoxyphenoxy)ethylamino)propoxy)-9H-carbazol-9-yl)-3-(2-(2-methoxyphenoxy)ethylamino)propan-2-ol is a complex organic molecule featuring a carbazole core substituted with two identical 2-(2-methoxyphenoxy)ethylamino-propanol side chains. This structure is characteristic of a carvedilol analogue or derivative. This compound is primarily investigated as a key intermediate in the synthesis of novel β-adrenergic receptor blockers (beta-blockers). Its structural framework, combining the carbazole moiety with the specific aminoalkoxy side chains, is designed to target cardiovascular diseases. Research focuses on its potential to modulate adrenergic receptors, aiming to develop new therapeutic agents for conditions like hypertension and heart failure with potentially improved efficacy or reduced side effects compared to existing drugs like carvedilol. As a research chemical, it is used in medicinal chemistry programs for structure-activity relationship (SAR) studies. Handling requires standard precautions for laboratory chemicals, and its use is strictly confined to research and development settings, not for human or veterinary therapeutic application.
    Physical Properties
    mg g kg ml l t