(S)-2-Amino-2-(thiophen-3-yl)acetic acid, CAS No. 1194-87-2

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

1194-87-2

Catalog No. EBD2215702

CAS 1194-87-2

Name (S)-2-Amino-2-(thiophen-3-yl)acetic acid

Get Quote

Basic Information

Synonyms: (S)-2-Amino-2-(thiophen-3-yl)aceticacid (s)-3-thienylglycine h-gly(3-thienyl)-oh l-alpha-(3-thienyl)glycine l-2-(3-thienyl)-glycine h-(3)thg-oh d-a-(3-thienyl)glycine l-a-(3-thienyl)glycine l-α-(3-thienyl)glycine

Molecular Formula: C6H7NO2S

Molecular Weight: 157.19

MDL Number: MFCD00079617

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives

Product Description:

L-α-(3-Thienyl)glycine, with CAS number 1194-87-2, is a non-proteinogenic amino acid derivative. Its structure features a thiophene ring (a five-membered heterocycle containing sulfur) attached to the alpha-carbon of a glycine backbone, with the L-configuration at the chiral center. This compound is a chiral building block of interest in medicinal chemistry. Its primary application is as a key synthetic intermediate in the research and development of pharmaceutical agents. The thiophene moiety is a privileged structure in drug design, often used as a bioisostere for phenyl rings to modulate pharmacokinetic properties. L-α-(3-Thienyl)glycine serves as a precursor for incorporating this heterocyclic amino acid motif into peptides or peptidomimetics, which are explored for various biological activities. As a specialized, non-natural amino acid derivative with a defined stereochemistry, it is primarily utilized in the synthesis of complex molecules for biological evaluation rather than as a bulk commodity or a general-purpose synthetic reagent.

Physical Properties

Boiling Point: 317.5 °C at 760 mmHg

Flash Point: 145.8 °C

Density: 1.418 g/cm3