Epristeride, CAS No. 119169-78-7

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119169-78-7

Catalog No. EBD11902

CAS 119169-78-7

Name Epristeride

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Basic Information

Synonyms: (17b)-17-[[(1,1-Dimethylethyl)amino]carbonyl]androsta-3,5-diene-3-carboxylicAcid (17beta)-17-(tert-Butylcarbamoyl)androsta-3,5-diene-3-carboxylicacid 119169-78-7 androsta-3,5-diene-3-carboxylicacid,17-[[(1,1-dimethylethyl)amino]carbonyl]-,(17beta)- 17-(tert-butylcarbamoyl)androsta-3,5-diene-3-carboxylicacid 17-N-tert-Butylcarboxamideandrost-3,5-diene-3-carboxylicacid (17b)-17-[[(1,1-Dimethylethyl)amino]carbonyl]-androsta-3,5-diene-3-carboxylicacid Epristeride

Molecular Formula: C25H37NO3

Molecular Weight: 399.57

Categories: Medicinal Chemistry > APIs and Their Salts > Urinary System Drugs Medicinal Chemistry > APIs and Their Salts > Endocrine & Metabolic Drugs

Product Description:

Epristeride is a synthetic 4-azasteroid compound, specifically a competitive and selective inhibitor of the enzyme steroid 5α-reductase type II. It is chemically known as N-tert-butyl-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide. Its primary and well-defined application is in the treatment of benign prostatic hyperplasia (BPH). By inhibiting the conversion of testosterone to the more potent androgen dihydrotestosterone (DHT) in the prostate gland, epristeride reduces prostate volume, alleviates urinary obstructive symptoms, and improves urinary flow rates. It has been approved and marketed as a pharmaceutical drug in several countries, including China. As a specific drug substance, epristeride is categorized as an active pharmaceutical ingredient (API). Its mechanism targets an endocrine pathway, placing it within the realm of drugs affecting the endocrine and metabolic systems, specifically for urological conditions.

Physical Properties

Boiling Point: 596°Cat760mmHg

Flash Point: 314.3°C

Density: 1.13g/cm3