(2S)-Methylglycidate, CAS No. 118712-39-3

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118712-39-3

Catalog No. EBD2224600

CAS 118712-39-3

Name (2S)-Methylglycidate

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Basic Information

Synonyms: (2S)-Methylglycidate Methyl(2S)-glycidate methyl(2S)-oxirane-2-carboxylate

Molecular Formula: C4H6O3

Molecular Weight: 102.09

Categories: Materials Chemistry > Polymers and Macromolecular Materials > Epoxy and Epoxy Resin Precursors Synthetic Chemistry > Organic Building Blocks > Other Organic Building Blocks

Product Description:

(S)-Methyl glycidate is a chiral epoxide derivative, specifically the methyl ester of (S)-glycidic acid. It is a colorless to pale yellow liquid with the molecular formula C4H6O3. This compound is characterized by its reactive oxirane (epoxide) ring and an ester functional group, making it a versatile chiral building block. Its primary industrial application is as a key chiral intermediate in the synthesis of various pharmaceuticals, particularly beta-blockers and other cardiovascular drugs. The (S)-enantiomer is crucial for imparting the desired biological activity. Beyond pharmaceuticals, it serves as a monomer or precursor in polymer chemistry for producing specialty epoxy resins and functional polymers where chirality or specific reactivity is required. The compound is moisture-sensitive and typically stored under inert conditions. It is commercially available from fine chemical suppliers for research and development purposes in asymmetric synthesis and advanced material fabrication.

Physical Properties

Boiling Point: 97.45 °C at 760 mmHg

Flash Point: 72 °C

Density: 1.166 g/mL at 25 °C(lit.)

Refractivity: n20/D 1.42(lit.)

Storage: 2-8°C

Safety Information

Packing Level: III

Hazard Category: /

Transport Codes: 1993