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    1184999-47-0

    Catalog No. EBD3313914

    CAS 1184999-47-0

    Name (1R,2R)-2-(diMethylaMino)cyclopentanol

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    Basic Information

    Synonyms: (1R,2R)-2-(diMethylaMino)cyclopentanol trans-2-(Dimethylamino)cyclopentanol

    Molecular Formula: C7H15NO

    Molecular Weight: 129.2

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (1R,2R)-2-(Dimethylamino)cyclopentanol is a chiral amino alcohol derivative characterized by a cyclopentane ring substituted with a dimethylamino group and a hydroxyl group at adjacent positions, both in the *trans* configuration. This specific stereochemistry is crucial for its function as a key chiral building block. Its primary and most significant application is in the pharmaceutical industry as a chiral intermediate. It is notably utilized in the synthesis of complex drug molecules, particularly those targeting the central nervous system. For example, it serves as a critical precursor in the production of certain antiviral agents and other bioactive compounds where the rigid, defined stereochemistry of the cyclopentane scaffold is essential for binding to biological targets and achieving desired pharmacological activity. Beyond its role as a pharmaceutical intermediate, this compound is also a valuable chiral synthon in organic synthesis. The presence of both a basic tertiary amine and a hydroxyl group makes it useful in asymmetric catalysis, as a ligand precursor, or for constructing more complex chiral architectures in medicinal chemistry research.
    Physical Properties
    mg g kg ml l t