(3S,4R)-tert-Butyl 3-fluoro-4-hydroxypiperidine-1-carboxylate, CAS No. 1174020-40-6

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

1174020-40-6

Catalog No. EBD2222846

CAS 1174020-40-6

Name (3S,4R)-tert-Butyl 3-fluoro-4-hydroxypiperidine-1-carboxylate

Get Quote

Basic Information

Synonyms: (3S,4R)-tert-Butyl3-fluoro-4-hydroxypiperidine-1-carboxylate (cis)-3-fluoro-4-hydroxypiperidine-1-carboxylicacidtert-butylester tert-butyl(3,4-cis)-3-fluoro-4-hydroxypiperidine-1-carboxylate 1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidine-3-carboxylicacid tert-butylcis-3-fluoro-4-hydroxy-piperidine-1-carboxylate 1-Boc-3S-fluoro-4R-piperidinol

Molecular Formula: C10H18FNO3

Molecular Weight: 219.25

Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Synthetic Chemistry > Organic Building Blocks > Amines Synthetic Chemistry > Organic Building Blocks > Phenols and Ethers Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

Product Description:

(3S,4R)-tert-Butyl 3-fluoro-4-hydroxypiperidine-1-carboxylate is a chiral, fluorine-containing piperidine derivative. Its structure features a tert-butoxycarbonyl (Boc) protecting group on the nitrogen, along with a fluorine atom and a hydroxyl group at the 3- and 4-positions, respectively, with defined (3S,4R) stereochemistry. This compound is primarily utilized as a key synthetic intermediate in medicinal chemistry, particularly for constructing complex drug candidates targeting the central nervous system (CNS) and other therapeutic areas. The presence of fluorine enhances metabolic stability and bioavailability, while the chiral hydroxyl group offers a handle for further functionalization. It is commonly employed in the synthesis of kinase inhibitors, receptor modulators, and other bioactive molecules.

Physical Properties