Oxacillin sodium salt, CAS No. 1173-88-2

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1173-88-2

Catalog No. EBD6538

CAS 1173-88-2

Name Oxacillin sodium salt

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Basic Information

Synonyms: 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylicacid,3,3-dimethyl-6-(5-methyl-3 5-methyl-3-phenyl-4-isoxazolylpenicillin,sodium bactocill bristopen brl1400 cryptocillin micropenin monosodiumoxacillin oxacillinsodium (2S,5R,6R)-3,3-Dimethyl-6-[(5-methyl-3-phenyl-1,2-oxazole-4-carbonyl)amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacidsodiumsalt Oxacillinsodiumsalt Oxacillinsodiumanhydrous Bactocilsodium Prostaphlinsodium OxabelSodiumsalt Sodiummethylphenylisoaxazolylpenicillin 3,3-dimethyl-6-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid (2S,5R,6R)-3,3-dimethyl-6-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid sodium3,3-dimethyl-6-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carbo

Molecular Formula: C19H18N3NaO5S

Molecular Weight: 423.42

MDL Number: MFCD00056864

Categories: Medicinal Chemistry > APIs and Their Salts > Anti-infectives Medicinal Chemistry > APIs and Their Salts > Nervous System Drugs

Product Description:

Oxacillin sodium salt is a semisynthetic, penicillinase-resistant penicillin antibiotic. It is the sodium salt of oxacillin, a beta-lactam antibiotic characterized by an isoxazolyl side chain, which confers resistance to degradation by staphylococcal beta-lactamase enzymes. Its primary and most significant application is as an active pharmaceutical ingredient (API) for the treatment of infections caused by penicillinase-producing staphylococci. It is specifically indicated for skin and soft tissue infections, respiratory tract infections, and other susceptible bacterial infections. While its core use is anti-infective, oxacillin has also been investigated in research contexts for potential effects within the central nervous system, particularly in models related to neuroinflammation and blood-brain barrier function, though this is not its primary clinical indication. The compound is typically administered via intramuscular or intravenous injection. As with other penicillins, hypersensitivity reactions are a key safety concern. It is commercially available as a sterile powder for injection.

Physical Properties

Melting Point: 188 °C

Boiling Point: 686.8 °C at 760 mmHg

Flash Point: 369.2 °C

Storage: 2-8°C

Analytical Data

Appearance: Crystalline