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    1171125-92-0

    Catalog No. EBD3726349

    CAS 1171125-92-0

    Name tert-butyl (3S,4R)-4-amino-3-methoxypiperidine-1-carboxylate

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    Basic Information

    Synonyms: 2-Methyl-2-propanyl(3S,4R)-4-amino-3-methoxy-1-piperidinecarboxylate tert-butyl(3S,4R)-4-amino-3-methoxypiperidine-1-carboxylate

    Molecular Formula: C11H22N2O3

    Molecular Weight: 230.31

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (3S,4R)-N-BOC-4-Amino-3-methoxypiperidine is a chiral piperidine derivative featuring both a Boc-protected amino group and a methoxy substituent. This compound serves as a crucial chiral building block in pharmaceutical synthesis. Its defined stereochemistry at the 3- and 4-positions makes it a valuable intermediate for constructing complex molecules with specific three-dimensional structures. The primary application of this compound is in the research and development of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system (CNS) and other therapeutic areas. It is frequently employed as a key intermediate in the synthesis of drug candidates where the piperidine scaffold is a core structural element. The Boc protecting group allows for selective deprotection and further functionalization under mild conditions, facilitating multi-step synthetic routes. As a specialty chiral amine, it is not a commodity chemical but is produced and supplied for advanced medicinal chemistry and process chemistry applications. Its use underscores the importance of stereochemically defined intermediates in modern drug discovery for achieving desired biological activity and pharmacokinetic profiles.
    Physical Properties
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