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    116632-53-2

    Catalog No. EBD2051847

    CAS 116632-53-2

    Name 7-Bromoquinolin-2-amine

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    Basic Information

    Synonyms: 7-bromoquinolin-2-amine

    Molecular Formula: C9H7BrN2

    Molecular Weight: 223.07

    MDL Number: MFCD08062656

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    7-Bromoquinolin-2-amine is an organic compound featuring a quinoline core substituted with a bromine atom at the 7-position and an amino group at the 2-position. This structure makes it a versatile and valuable heterocyclic building block in synthetic chemistry. Its primary application is as a key intermediate in the pharmaceutical industry. The presence of both a halogen (bromine) and an amine group on the quinoline scaffold allows for further functionalization through cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitutions. This compound is specifically cited in patent literature and research for the synthesis of various biologically active molecules, including kinase inhibitors and other potential therapeutic agents targeting cancer and other diseases. Due to its well-defined reactive sites, it is also employed in academic and industrial research as a standard starting material for constructing more complex nitrogen-containing heterocycles and functionalized quinolines, underscoring its dual role as a specialized pharmaceutical intermediate and a general synthetic building block.
    Physical Properties

    Boiling Point: 362.429°C at 760 mmHg

    Flash Point: 172.991°C

    Density: 1.649g/cm3

    mg g kg ml l t