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    114748-70-8

    Catalog No. EBD3333469

    CAS 114748-70-8

    Name (2S,5R)-5-(4-amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydro-2-Furanmethanol

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    Basic Information

    Synonyms: (2S,5R)-5-(4-amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydro-2-Furanmethanol

    Molecular Formula: C11H13IN4O2

    Molecular Weight: 360.15

    Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Saccharides, Nucleosides, and Nucleotides Medicinal Chemistry > Pharmaceutical Intermediates > Drug Synthesis Building Blocks

    Product Description:
    7-I-7-deaza-2'-deoxyadenosine is a modified nucleoside analog. Its structure features a 7-deaza-7-iodo modification on the purine base and a 2'-deoxyribose sugar moiety. This specific halogenation at the 7-position of the deazaadenine ring is a key structural alteration. This compound serves as a crucial intermediate in the synthesis of nucleoside-based antiviral and anticancer agents. It is particularly important in the development of chain-terminating inhibitors for viral polymerases. For instance, it is a key precursor in the synthesis of certain 2'-deoxy-7-deazapurine nucleoside analogs investigated for their biological activity. As a specialized building block, it is used in medicinal chemistry research to explore structure-activity relationships and to create novel therapeutic candidates targeting DNA/RNA synthesis pathways. Its handling requires standard precautions for potentially bioactive organic compounds.
    Physical Properties
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