3-Amino-4-hydroxybiphenyl, CAS No. 1134-36-7

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1134-36-7

Catalog No. EBD53537

CAS 1134-36-7

Name 3-Amino-4-hydroxybiphenyl

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Basic Information

Synonyms: 2-Amino-4-phenylphenol [1,1'-biphenyl]-4-ol,3-amino- 214-484-8 3-aminobiphenyl-4-ol labotest-bblt00089250 1’-biphenyl)-4-ol,3-amino-( 1’-biphenyl]-4-ol,3-amino-[ 2-hydroxy-5-phenylaniline 3-amino-(1,1’-biphenyl)-4-ol 3-Amino-1,1'-biphenyl-4-ol 3-Amino-4-hydroxybiphenyl

Molecular Formula: C12H11NO

Molecular Weight: 185.22

MDL Number: MFCD00059187

Categories: Synthetic Chemistry > Organic Building Blocks > Amines Synthetic Chemistry > Organic Building Blocks > Phenols and Ethers Materials Chemistry > Optoelectronic and Organic Semiconductor Materials > OLED and Organic Optoelectronic Precursors

Product Description:

3-Amino-4-hydroxybiphenyl is an aromatic amine and phenol derivative featuring a biphenyl core with an amino group at the 3-position and a hydroxyl group at the 4-position. This bifunctional structure makes it a valuable small molecule fragment in medicinal chemistry, particularly for constructing bioactive molecules targeting kinases, G protein-coupled receptors (GPCRs), or other therapeutic targets where the biphenyl scaffold is a privileged structure. As a synthetic building block, it serves as a key intermediate in the preparation of pharmaceuticals, agrochemicals, and functional materials. The amino and hydroxyl groups allow for further derivatization via acylation, alkylation, or coupling reactions, enabling the synthesis of complex heterocycles or conjugated systems. It is also utilized in the development of dyes, pigments, and organic electronic materials due to its electron-rich aromatic system.

Physical Properties

Melting Point: 198-202 °C(lit.)

Boiling Point: 356 °C at 760 mmHg

Flash Point: 169.1 °C

Density: 1.191 g/cm3