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    112708-89-1

    Catalog No. EBD3554440

    CAS 112708-89-1

    Name Cyclohexanol, 2-(methylamino)-, (1S,2R)-

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    Basic Information

    Synonyms: Cyclohexanol,2-(methylamino)-,(1S,2R)-

    Molecular Formula: C7H15NO

    Molecular Weight: 129.2

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (1S,2R)-2-(Methylamino)cyclohexan-1-ol is a chiral amino alcohol derivative featuring a cyclohexane ring substituted with both a hydroxyl group and a methylamino group. Its specific stereochemistry, defined as (1S,2R), makes it a valuable chiral building block in asymmetric synthesis. This compound serves as a key chiral intermediate in the pharmaceutical industry. Its primary application is in the synthesis of various active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. For instance, it is a crucial precursor in the production of certain antidepressants and other neuroactive compounds, where its defined stereochemistry is essential for biological activity and receptor binding. As a bifunctional molecule containing both amine and alcohol groups, it is also utilized in organic synthesis for constructing complex molecular architectures. Its chirality allows it to act as a chiral auxiliary or ligand in certain catalytic reactions, although its primary commercial significance remains tied to its role in drug development.
    Physical Properties
    mg g kg ml l t