(+)-Penicillamine, CAS No. 1113-41-3

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1113-41-3

Catalog No. EBD3314116

CAS 1113-41-3

Name (+)-Penicillamine

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Basic Information

Synonyms: 3-mercapto-l-valine 3-thiol-valine 3,3-dimethyl-l-cysteine l-beta,beta-dimethylcysteine l-beta-mercaptovaline l-(+)-penicillamine l-penicillamine l(+)-2-amino-3-mercapto-3-methylbutanoicacid (+)-Penicillamine L-(+)-β-mercaptovaline 1113-41-3 ALPHA-AMINO-BETA-METHYL-BETA-MERCAPTOBUTYRICACID valine,3-mercapto- 3-sulfanyl-L-valine L(+)-Penicillamine

Molecular Formula: C5H11NO2S

Molecular Weight: 149.21

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives Medicinal Chemistry > APIs and Their Salts > Bone and Joint Disease Drugs

Product Description:

(+)-Penicillamine is the L-enantiomer of penicillamine, a sulfur-containing amino acid structurally derived from the hydrolysis of penicillin. It features a thiol group and a dimethyl-substituted carbon backbone, making it a chiral molecule with specific biological activity. Its primary application is as a pharmaceutical active ingredient (API) for treating Wilson's disease, where it chelates excess copper, and as a disease-modifying antirheumatic drug (DMARD) for severe rheumatoid arthritis. It also serves as a key biochemical reagent in research, particularly for studying metal chelation and thiol-disulfide exchange reactions.

Physical Properties

Melting Point: 206 °C (dec.)(lit.)

Boiling Point: 251.8°Cat760mmHg

Flash Point: 106.1°C

Density: 1.204g/cm3

Refractivity: 63 ° (C=1, 1mol/L NaOH)

Storage: Store at RT.