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    1110772-22-9

    Catalog No. EBD2205523

    CAS 1110772-22-9

    Name TRANS-3-AMINOCYCLOHEXAN-1-OL,

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    Basic Information

    Synonyms: Cyclohexanol,3-amino-,(1R,3S)- TRANS-3-AMINOCYCLOHEXAN-1-OL, (1R,3S)-3-Aminocyclohexanol

    Molecular Formula: C6H13NO

    Molecular Weight: 115.17

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (1R,3S)-3-Aminocyclohexanol is a chiral amino alcohol compound featuring both an amino group and a hydroxyl group on a cyclohexane ring. Its specific stereochemistry, with the amino group in the equatorial position and the hydroxyl group in the axial position (or vice-versa depending on the chair conformation), makes it a valuable chiral building block. This compound is primarily utilized as a key chiral intermediate in pharmaceutical synthesis. Its structure serves as a core scaffold or a functional handle for constructing more complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). The presence of two functional groups allows for selective derivatization, enabling its incorporation into drug candidates targeting various therapeutic areas. As a bifunctional chiral synthon, it is also relevant in organic synthesis for constructing cyclic systems and in asymmetric catalysis as a precursor for chiral ligands or auxiliaries. Its defined stereochemistry is crucial for imparting desired biological activity or stereoselectivity in synthetic routes.
    Physical Properties
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