Entecavir intermediate N3, CAS No. 110567-22-1

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110567-22-1

Catalog No. EBD11509

CAS 110567-22-1

Name Entecavir intermediate N3

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Basic Information

Synonyms: (1S,2R,3S,5R)-3-(Phenymethyloxy)-2-(phenylmethoxy)methyl-6-oxabicyclo[3.1.0]hexane [1S-(1a,2a,3,5a)]-3-(Phenylmethoxy)-2-[(phenylmethoxy)methyl]-6-oxabicyclo[3.1.0]hexane EntecavirintermediateN3 (1S,2R,3S,5R)-3-(benzyloxy)-2-((4-methylbenzyloxy)methyl)-6-oxabicyclo[3.1.0]hexane Entecavirintermediate3 (1S,2R,3S,5R)-3-(benzyloxy)-2-[(benzyloxy)methyl]-6-oxabicyclo[3.1.0]hexane ENT-3 (1S,2R,3S,5R)-3-(Phenylmethoxy)-2-[(phenylmethoxy)methyl]-6-oxabicyclo[3.1.0]hexane

Molecular Formula: C20H22O3

Molecular Weight: 310.39

MDL Number: MFCD09750952

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > Pharmaceutical Intermediates > Drug Synthesis Building Blocks

Product Description:

The compound with CAS number 110567-22-1 is a key intermediate in the synthesis of Entecavir, a potent nucleoside analogue used as an antiviral medication for the treatment of chronic hepatitis B virus (HBV) infection. Its specific role in the synthetic pathway is crucial for constructing the core structure of the final active pharmaceutical ingredient (API). As an Entecavir intermediate, its primary and exclusive industrial application is in the pharmaceutical manufacturing process. It is not a general-purpose building block but a specialized synthon designed for a specific drug synthesis. The production and quality control of this intermediate are directly linked to the efficacy and safety of the final drug product. This intermediate falls under the category of pharmaceutical intermediates and is specifically a heterocyclic building block due to the presence of the cyclopentyl ring fused with a heterocyclic system, which is characteristic of nucleoside analogues. Its handling requires adherence to standard laboratory safety protocols for fine chemicals.

Physical Properties

Boiling Point: 427.928 °C at 760 mmHg

Flash Point: 145.852 °C

Density: 1.17