Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

    OK
    Get Quote Login
    110199-16-1

    Catalog No. EBD6738

    CAS 110199-16-1

    Name (R)-4-Isopropylthiazolidine-2-thione

    Get Quote
    Basic Information

    Synonyms: (R)-4-Isopropyl-1,3-thiazolidine-2-thione (R)-4-Isopropylthiazolidine-2-thione (4R)-4-(1-methylethyl)-1,3-thiazolidine-2-thione

    Molecular Formula: C6H11NS2

    Molecular Weight: 161.29

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates

    Product Description:
    (R)-4-Isopropylthiazolidine-2-thione is a chiral heterocyclic compound featuring a thiazolidine-2-thione core with an isopropyl substituent at the 4-position. This specific stereoisomer is a valuable building block in asymmetric synthesis due to its well-defined stereochemistry and the presence of sulfur-containing functional groups. Its primary application is in the pharmaceutical industry as a chiral intermediate or auxiliary. The compound is notably used in the synthesis of complex molecules, including certain antibiotics and other bioactive agents where the introduction of a chiral center is critical. The thiazolidine-2-thione moiety can serve as a precursor for thiols or as a ligand in metal-catalyzed reactions, facilitating the construction of enantiomerically enriched targets. While not a commodity chemical, it is a specialized reagent for research and development in medicinal chemistry. Its utility stems from its ability to impart chirality and participate in diverse chemical transformations, making it a key tool for synthesizing optically active pharmaceutical candidates.
    Physical Properties

    Melting Point: 69-71 °C

    mg g kg ml l t