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    110013-19-9

    Catalog No. EBD14920

    CAS 110013-19-9

    Name (S)-Pyrrolidin-3-ylmethanol

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    Basic Information

    Synonyms: (S)-3-Pyrrolidinemethanol 3-(S)-Hydroxymethylpyrrolidine (3S)-pyrrolidin-3-ylmethanol (3S)-3-Pyrrolidinemethanol (S)-Pyrrolidin-3-ylmethanol

    Molecular Formula: C5H11NO

    Molecular Weight: 101.15

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (S)-Pyrrolidin-3-ylmethanol is a chiral heterocyclic building block featuring a pyrrolidine ring substituted with a hydroxymethyl group at the 3-position. It is a versatile intermediate in organic synthesis, particularly valued for its stereochemistry and the presence of both amine and alcohol functional groups. This compound is widely utilized in pharmaceutical research as a key chiral synthon for the construction of bioactive molecules. Its primary application lies in the synthesis of various drug candidates, including protease inhibitors, kinase inhibitors, and other therapeutic agents where the (S)-pyrrolidine scaffold is a critical pharmacophore. The molecule serves as a precursor for more complex structures in medicinal chemistry. As a bifunctional molecule, it can undergo reactions at both the amine and alcohol sites, enabling its incorporation into diverse molecular architectures. It is commercially available from suppliers specializing in fine chemicals and chiral intermediates for drug discovery and development.
    Physical Properties

    Boiling Point: 176.136 °C at 760 mmHg

    Flash Point: 89.626 °C

    Density: 0.979 g/cm3

    mg g kg ml l t