(3R,4S)-4-aminooxan-3-ol hydrochloride is a chiral, heterocyclic building block featuring a tetrahydropyran (oxane) ring substituted with an amino group and a hydroxyl group at the 4- and 3-positions, respectively. It is supplied as a hydrochloride salt to enhance stability and handling properties. This compound is a key synthetic intermediate in the production of novel antibacterial agents. It serves as a crucial precursor in the synthesis of advanced macrolide antibiotics, specifically those targeting drug-resistant bacterial strains. Its defined stereochemistry is essential for constructing the complex macrocyclic core and achieving the desired biological activity. The primary application of this intermediate is in the research and development of next-generation anti-infective drugs. Its use is documented in patent literature related to the synthesis of potent ketolide and fluoroketolide antibiotics designed to overcome bacterial resistance mechanisms.