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    1093351-24-6

    Catalog No. EBD3739308

    CAS 1093351-24-6

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    Basic Information

    Molecular Formula: C2H2O4*C14H26N2O4

    Molecular Weight: 376.41

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Medicinal Chemistry > Biochemicals and Life Science Reagents > Peptides and Peptidomimetics

    Product Description:
    (1S,3R,4S)-4-Amino-3-((tert-butoxycarbonyl)amino)cyclohexanecarboxylic acid ethyl ester oxalate is a chiral cyclohexane derivative featuring both a Boc-protected amino group and an ethyl ester moiety. Its structure is characterized by three defined stereocenters, making it a valuable non-natural, conformationally constrained amino acid building block. This compound is primarily utilized as a key chiral intermediate in pharmaceutical research and development. Its main application lies in the synthesis of complex molecules, particularly as a constrained scaffold for designing peptidomimetics and novel drug candidates. The presence of orthogonal protecting groups (Boc and ethyl ester) allows for selective deprotection and further functionalization, facilitating its incorporation into larger molecular architectures aimed at modulating biological targets. The oxalate salt form enhances its crystallinity and stability, which is beneficial for handling, purification, and storage in a laboratory or process development setting. Its specific stereochemistry is crucial for imparting desired three-dimensional interactions in the final bioactive compounds.
    Physical Properties
    mg g kg ml l t