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    1092304-85-2

    Catalog No. EBD2338220

    CAS 1092304-85-2

    Name 8-bromoquinolin-2-amine

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    Basic Information

    Molecular Formula: C9H7BrN2

    Molecular Weight: 223.07

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    8-Bromoquinolin-2-amine is a heterocyclic organic compound featuring a quinoline scaffold substituted with a bromine atom at the 8-position and an amino group at the 2-position. This structure makes it a versatile and valuable bifunctional building block in synthetic chemistry. Its primary application is in medicinal chemistry as a key intermediate for the synthesis of various biologically active molecules. The bromine atom serves as a handle for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig), while the amino group can be further functionalized or act as a coordinating site. It is notably used in the research and development of kinase inhibitors, particularly as a precursor for compounds targeting specific protein kinases involved in disease pathways. Due to its well-defined reactivity and the privileged quinoline pharmacophore, it is widely employed in the construction of compound libraries for drug discovery. It is commercially available as a high-purity reagent for research purposes.
    Physical Properties
    mg g kg ml l t