7-Quinolinecarboxylic acid, CAS No. 1078-30-4

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1078-30-4

Catalog No. EBD958

CAS 1078-30-4

Name 7-Quinolinecarboxylic acid

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Basic Information

Synonyms: Quinoline-7-carboxylicacid akosbbs-00005341 7-quinolinecarboxylicacid,98% 7-carboxyquinoline quinolin-7-carboxylicacid 7-carboxyquinoline,7-carboxy-1-azanaphthalene 7-quinolinecarboxylicacid,95+% 7-Quinolinecarboxylicacid

Molecular Formula: C10H7NO2

Molecular Weight: 173.17

MDL Number: MFCD00047617

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Carboxylic Acids and Esters

Product Description:

7-Quinolinecarboxylic acid is an organic compound featuring a quinoline ring system substituted with a carboxylic acid group at the 7-position. It is a white to off-white crystalline powder with a molecular formula of C10H7NO2. This compound serves as a versatile and important heterocyclic building block in medicinal chemistry. Its primary application is as a key intermediate in the synthesis of various pharmaceutical agents. Notably, it is a crucial precursor in the production of certain quinolone and fluoroquinolone antibiotics, where the quinoline core is a fundamental pharmacophore. The carboxylic acid group provides a handle for further chemical modifications and derivatizations. Beyond its role in drug synthesis, 7-quinolinecarboxylic acid is also utilized in the development of metal-organic frameworks (MOFs) and as a ligand in coordination chemistry due to its chelating ability. It is commercially available from chemical suppliers for research and development purposes.

Physical Properties

Boiling Point: 348.7 °C at 760 mmHg

Flash Point: 164.7 °C

Density: 1.339 g/cm3