boc-D-Lys-OH, CAS No. 106719-44-2

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106719-44-2

Catalog No. EBD2205462

CAS 106719-44-2

Name boc-D-Lys-OH

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Basic Information

Synonyms: (2R)-6-ammonio-2-[(tert-butoxycarbonyl)amino]hexanoate N-α-Boc-D-lysine N2-Boc-D-lysine Nα-(tert-butoxycarbonyl)-D-lysine boc-D-Lys-OH N~2~-(tert-butoxycarbonyl)-L-lysine

Molecular Formula: C11H22N2O4

Molecular Weight: 246.3

MDL Number: MFCD00076956

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Drug Synthesis Building Blocks Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives

Product Description:

N-(tert-Butoxycarbonyl)-D-lysine is a protected derivative of the essential amino acid D-lysine, featuring a tert-butoxycarbonyl (Boc) group on the α-amino group. This white to off-white crystalline powder is a key chiral building block in organic synthesis and peptide chemistry. Its primary application is in the pharmaceutical industry as a crucial intermediate for the solid-phase and solution-phase synthesis of peptides and peptidomimetics. The Boc protecting group is stable under basic conditions and can be selectively removed under mild acidic conditions, making this compound invaluable for constructing complex peptide sequences, including those with D-amino acids for enhanced metabolic stability. It is specifically used in the synthesis of various bioactive peptides and potential therapeutic agents. As a derivative of D-lysine, it also serves as a biochemical reagent in life science research for studying enzyme specificity, protein structure, and for preparing custom amino acid analogs. Standard safety precautions for handling fine chemicals should be observed.

Physical Properties

Melting Point: 205-210 °C

Boiling Point: 410.5 °C at 760 mmHg

Flash Point: 202 °C

Density: 1.113 g/cm3

Storage: 2-8°C