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    106463-17-6

    Catalog No. EBD2185027

    CAS 106463-17-6

    Name (R)-5-(2-((2-(2-Ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide hydrochloride

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    Basic Information

    Synonyms: (R)-5-(2-((2-(2-Ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamidehydrochloride TamsulosinHydrochloride TamsulosinHCL 5-[(2R)-2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamidehydrochloride 5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonamidehydrochloride 5-(2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl)-2-methoxybenzenesulfonamidehydrochloride (-)-(R)-5-[2-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamidehydrochloride Tamuzosinhydrochloride

    Molecular Formula: C20H29ClN2O5S

    Molecular Weight: 444.97

    MDL Number: MFCD00922997

    Categories: Medicinal Chemistry > APIs and Their Salts > Urinary System Drugs

    Product Description:
    Tamsulosin hydrochloride is a selective α1-adrenergic receptor antagonist. It is a white to off-white crystalline powder with the chemical name (R)-5-[2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide hydrochloride. Its primary and well-established application is as an active pharmaceutical ingredient (API) for the treatment of benign prostatic hyperplasia (BPH). It works by relaxing the smooth muscle in the prostate and bladder neck, thereby improving urine flow and reducing symptoms of BPH. It is specifically selective for the α1A-adrenergic receptor subtype, which is predominant in the prostate. Tamsulosin hydrochloride is typically formulated into oral dosage forms, such as modified-release capsules. It is a key therapeutic agent in urology and is widely used in clinical practice under various brand names.
    Physical Properties

    Melting Point: 228-230°C

    Boiling Point: 595.5 °C at 760 mmHg

    Flash Point: 313.9 °C

    Storage: room temp

    Analytical Data

    Appearance: white to off-white solid

    mg g kg ml l t