(R)-2-Aminobutanamide hydrochloride, CAS No. 103765-03-3

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103765-03-3

Catalog No. EBD2212814

CAS 103765-03-3

Name (R)-2-Aminobutanamide hydrochloride

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Basic Information

Synonyms: (R)-2-Aminobutanamidehydrochloride (R)-(-)-2-AMINOBUTANAMIDEHYDROCHLORIDE (R)-2-AminobutanamideHCl (R)-2-Aminobutyramidehydrochloride (2R)-2-aminobutanamidehydrochloride

Molecular Formula: C4H11ClN2O

Molecular Weight: 138.6

MDL Number: MFCD09265126

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

(R)-(-)-2-Aminobutyramide hydrochloride is a chiral amine derivative, specifically the hydrochloride salt of (R)-2-aminobutyramide. It is a white to off-white crystalline powder. This compound serves as a crucial chiral building block in pharmaceutical synthesis. Its primary application is as a key intermediate in the production of Levetiracetam, a widely used antiepileptic drug (AED) belonging to the racetam class. The (R)-configuration of the molecule is essential for imparting the desired biological activity to the final API. It is also utilized in the synthesis of other active pharmaceutical ingredients (APIs) and chiral ligands. As a chiral synthon, it is valued for its role in asymmetric synthesis and the construction of molecules with specific stereochemistry. Handling requires standard precautions for amine salts, including avoiding inhalation and contact with skin or eyes.

Physical Properties

Melting Point: 258-262 °C

Boiling Point: 274.2 °C at 760 mmHg

Flash Point: 119.6 °C