Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

    OK
    Get Quote Login
    1029716-44-6

    Catalog No. EBD219465

    CAS 1029716-44-6

    Name 1-(1-Ethoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

    Get Quote
    Basic Information

    Synonyms: 1-(1-Ethoxyethyl)-1H-Pyrazole-4-BoronicAcidPinacolEster (1-(1-ETHOXYETHYL)-1H-PYRAZOL-4-YL)BORONICACIDPINACOLESTER 1-(1-Ethoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

    Molecular Formula: C13H23BN2O3

    Molecular Weight: 266.14

    Categories: Synthetic Chemistry > Organic Building Blocks > Boronic Acids and Boronic Esters

    Product Description:
    1-(1-Ethoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole is a specialized organic compound featuring a pyrazole ring substituted with both a protected boronic ester group (as a pinacol boronate) and a 1-ethoxyethyl protecting group on the adjacent nitrogen. This structure combines two key functionalities: the boronic ester is a crucial handle for Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern C-C bond formation in medicinal and materials chemistry, while the N-protecting group modulates reactivity and solubility. Its primary application is as a versatile synthetic building block, particularly in pharmaceutical research and development. The molecule serves as a key intermediate for constructing more complex heterocyclic scaffolds. The protected boronate allows for precise introduction of the pyrazole moiety into target molecules, facilitating the synthesis of potential drug candidates, especially those requiring specific substitution patterns on the pyrazole core. The presence of the protecting group makes it a more stable and handleable reagent compared to its unprotected analogues. As a research chemical, it is supplied in high purity for laboratory use. Handling requires standard precautions for organoboron compounds and should be conducted in a well-ventilated fume hood, avoiding moisture to prevent decomposition of the boronic ester functionality.
    Physical Properties
    mg g kg ml l t