9-(2-acetyloxyethoxymethyl)guanine, CAS No. 102728-64-3

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

102728-64-3

Catalog No. EBD236654

CAS 102728-64-3

Name 9-(2-acetyloxyethoxymethyl)guanine

Get Quote

Basic Information

Synonyms: 9-(2-acetyloxyethoxymethyl)guanine 9-(2-acetoxyethoxy)methylguanine 9-<(2-acetoxyethoxy)methyl>-2-amino-1,9-dihydro-6H-purin-6-one 9-<(2-acetoxyethoxy)methyl>guanine 9-(2-acetoxyethoxymethyl)-guanine 9-(2-Acetoxyethoxymethyl)guanine monoacetylacyclovir 9-(2'-ACETOXYETHOXYMETHYL)-GUANINE 2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethylacetate 6H-purin-6-one,9-[[2-(acetyloxy)ethoxy]methyl]-2-amino-1,9-dihydro- 2-[(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)methoxy]ethylacetate

Molecular Formula: C10H13N5O4

Molecular Weight: 267.24

MDL Number: MFCD00871663

Categories: Medicinal Chemistry > Drug Impurities and Reference Standards > Impurity Standards Medicinal Chemistry > Biochemicals and Life Science Reagents > Saccharides, Nucleosides, and Nucleotides

Product Description:

9-(2-Acetyloxyethoxymethyl)guanine, with CAS number 102728-64-3, is a guanine derivative. It is structurally characterized by a guanine base linked to a 2-acetoxyethoxymethyl group at the N9 position. This specific modification distinguishes it from the parent nucleoside. This compound is primarily known and utilized as a specified impurity in the pharmaceutical industry. It is officially recognized as "Acyclovir Impurity A" or "Acyclovir Related Compound A" in pharmacopeial standards (e.g., USP, EP). Its primary application is as a reference standard for quality control and analytical purposes during the manufacturing and testing of the antiviral drug Acyclovir and its related formulations. Accurate quantification of this impurity is critical for ensuring drug safety, efficacy, and regulatory compliance. As a guanine analog, it falls within the broader category of nucleobase derivatives. While its defined role is as a pharmaceutical impurity standard, its core structure relates it to modified nucleosides, which are of interest in biochemical and life science research.

Physical Properties

Boiling Point: 565.4 °C at 760 mmHg

Flash Point: 295.7 °C

Density: 1.61 g/cm3