N-Boc-N\'-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine, CAS No. 102185-38-6

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

102185-38-6

Catalog No. EBD51978

CAS 102185-38-6

Name N-Boc-N\'-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine

Get Quote

Basic Information

Synonyms: N(alpha)-boc-N(omega)-mtr-L-arginine na-T-boc-N-omega-(4-methoxy-2,3,6-*trimethylbenze Boc-Arg(Mts)-OH (2S)-2-(tert-butoxycarbonylamino)-5-[[N-(2,4,6-trimethylphenyl)sulfonylcarbamimidoyl]amino]pentanoicacid N-alpha-BOC-N(G)-Mesitylenesulfonyl-L-Arginine N-alpha-T-butoxycarbonyl-N-OMEGA-(2-Mesitylenesulfonyl)-L-Arginine2-Mesitylenesulfonyl N-alpha-TERT-BUTYLOXYCARBONYL-N'-(Mesitylene-2-sulfonyl)-L-Arginine N-alpha-T-BOC-N-OMEGA-Mesitylene-sulfonyl-L-ArginineMONOCYCLOHEXYLAMMONIUMSALT BOC-N-OMEGA-(Mesitylene-2-sulfonyl)-L-Arginine BOC-L-Arginine(MTS) BOC-L-ARG(MTS)-OH BOC-L-ARG(MTS) N-Boc-N\'-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine N-alpha-TERT-BUTYLOXYCARBONYL-N'-(Mesitylene-2-sulfon

Molecular Formula: C21H34N4O7S

Molecular Weight: 486.58

MDL Number: MFCD00057790

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Peptides and Peptidomimetics

Product Description:

N-Boc-N'-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine is a protected derivative of the amino acid L-arginine. It features two orthogonal protecting groups: the acid-labile tert-butoxycarbonyl (Boc) group on the α-amino function and the base-labile 4-methoxy-2,3,6-trimethylbenzenesulfonyl (Mtr) group on the guanidino side chain. This specific combination makes it a crucial building block in solid-phase peptide synthesis (SPPS), particularly in the Boc/Bzl strategy. Its primary application is in the synthesis of peptides containing arginine residues. The Mtr group effectively protects the highly basic and nucleophilic guanidino group during peptide chain assembly, preventing side reactions. It can be selectively removed under conditions (e.g., with hydrogen fluoride or trifluoromethanesulfonic acid) that are compatible with the Boc strategy, allowing for the final deprotection and cleavage of the synthesized peptide from the resin. This reagent is essential for producing research peptides and potential therapeutic agents where precise arginine incorporation is required. The compound is a specialty chemical used almost exclusively in peptide chemistry research and development. Handling requires standard precautions for laboratory chemicals, and it should be stored under inert conditions to maintain stability.

Physical Properties