(R)-4-BENZYL-2-OXAZOLIDINONE, CAS No. 102029-44-7

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102029-44-7

Catalog No. EBD3039495

CAS 102029-44-7

Name (R)-4-BENZYL-2-OXAZOLIDINONE

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Basic Information

Synonyms: RBOX (R)-4-BENZYL-2-OXAZO 4-BENZYL-2-0XAZOLIDINONE 4-R-BENZYL-2-OXAZOLIDINONE (4R)-BENZYLOXAZOLIDIN-2-ONE (R)-(+)-4-Benzyl-2-oxazolidinone (R)-4-Benzyl-1,3-oxazolidin-2-one 4(R)-benzyl-oxazolidin-2-one (4R)-4-benzyl-1,3-oxazolidin-2-one 2-Oxazolidinone,4-(phenylmethyl)-,(4R)- 2-Oxazolidinone,4-benzyl-,(R)- R-BOZ R-(4)-Benzyl-2-Oxazolidinone (R)-4-phenylmethyl-2-oxazolidone

Molecular Formula: C10H11NO2

Molecular Weight: 177.2

Categories: Synthetic Chemistry > Basic Synthetic Reagents > Chiral Auxiliaries and Resolution Reagents

Product Description:

(R)-4-Benzyl-2-oxazolidinone is a chiral auxiliary derived from oxazolidinone, featuring a benzyl substituent at the 4-position with R-configuration. It is widely utilized in asymmetric synthesis, particularly in Evansбп aldol reactions, alkylations, and Diels-Alder reactions, where it serves as a stereodirecting group to control the formation of new chiral centers. The compound is also employed as a chiral intermediate in the preparation of enantiomerically pure pharmaceuticals, including beta-lactam antibiotics and other bioactive molecules. Its high enantiomeric purity and stability under standard reaction conditions make it a valuable tool in both academic research and industrial process development.

Physical Properties

Melting Point: 88-90 °C

Boiling Point: 398.8 °C at 760 mmHg

Flash Point: 195 °C

Density: 1.176 g/cm3

Refractivity: 14.5 ° (C=5, MeOH)

Storage: 0-6°C

Analytical Data

Appearance: white to light yellow crystal powder