(R)-(+)-2-(Benzyloxy)propionic acid, CAS No. 100836-85-9

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100836-85-9

Catalog No. EBD219710

CAS 100836-85-9

Name (R)-(+)-2-(Benzyloxy)propionic acid

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Basic Information

Synonyms: (R)-(+)-2-Benzyloxypropionicacid O-Benzyl-D-lacticacid (2R)-2-(benzyloxy)propanoicacid (R)-(+)-2-Benzyloxypropanoicacid (R)-(+)-2-(Benzyloxy)propionicacid (R)-2-(Benzyloxy)propanoicacid

Molecular Formula: C10H12O3

Molecular Weight: 180.2

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Carboxylic Acids and Esters

Product Description:

(R)-(+)-2-Benzyloxypropanoic acid is a chiral carboxylic acid derivative characterized by a benzyl-protected secondary alcohol adjacent to the carboxylic acid group. It serves as a versatile chiral building block in organic synthesis, particularly valued for its (R)-configuration. Its primary application is as a key chiral intermediate in the pharmaceutical industry. It is notably used in the synthesis of chiral drugs and bioactive molecules, such as certain β-lactam antibiotics and other compounds where the introduction of a chiral α-alkoxy acid moiety is crucial. The benzyl group acts as a protecting group for the alcohol, which can be selectively removed at a later synthetic stage. This compound is commercially available as a high-purity material for research and development purposes. As with many organic acids, appropriate safety precautions should be observed during handling to avoid irritation.

Physical Properties

Melting Point: 52-55 °C

Boiling Point: 328.2°Cat760mmHg

Flash Point: 130.4°C

Density: 1.15g/cm3