2-Iodo-phenylboronic acid is an organoboron compound featuring both an arylboronic acid group and an ortho-substituted iodine atom on the benzene ring. This bifunctional structure makes it a versatile building block in synthetic organic chemistry, particularly in cross-coupling reactions. Its primary application is as a key intermediate in Suzuki-Miyaura cross-coupling reactions. The boronic acid group readily participates in palladium-catalyzed coupling with aryl or vinyl halides, while the iodine atom serves as an excellent leaving group for subsequent functionalization via other metal-catalyzed reactions (e.g., Sonogashira, Heck, or further Suzuki couplings). This dual reactivity allows for the sequential, orthogonal construction of complex biaryl and polyaryl structures, which are common scaffolds in pharmaceuticals, agrochemicals, and organic materials. The compound is typically handled under inert atmosphere due to the sensitivity of the boronic acid group and is used by researchers and process chemists for the synthesis of advanced intermediates. Its stability and commercial availability facilitate its use in library synthesis for drug discovery and material science research.