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    1003843-30-8

    Catalog No. EBD47594

    CAS 1003843-30-8

    Name N-Boc-2,6-diethyl-4-oxo-piperdine

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    Basic Information

    Synonyms: N-boc-2,6-diethyl-4-oxo-piperdine CIS-2,6-Diethyl-4-oxo-piperidine-1-carboxylicacidtert-butylester cis-2,6-Diethyl-4-oxopiperidine-1-carboxylicacidtert-butylester

    Molecular Formula: C14H25NO3

    Molecular Weight: 255.35

    MDL Number: MFCD12761614

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    N-Boc-2,6-diethyl-4-oxopiperidine is a protected piperidine derivative featuring a Boc (tert-butoxycarbonyl) group on the nitrogen and two ethyl substituents at the 2- and 6-positions, with a ketone at the 4-position. This specific substitution pattern makes it a valuable chiral or sterically defined building block. Its primary application is as a key intermediate in pharmaceutical research and development, particularly for the synthesis of complex drug candidates. The Boc-protected amine is a standard handle for peptide coupling and further functionalization, while the 4-oxo (ketone) group serves as a versatile site for reductive amination or Grignard reactions to introduce diverse side chains. This scaffold is relevant in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas. As a functionalized heterocycle, it falls under the category of specialized organic synthesis building blocks. Its defined structure is more specific than a generic amine, placing it appropriately within the heterocyclic intermediate class for drug discovery, with secondary utility as an advanced amine synthon in synthetic chemistry.
    Physical Properties

    Boiling Point: 340.907 °C at 760 mmHg

    Flash Point: 159.975 °C

    Density: 0.996 g/cm3

    mg g kg ml l t