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    1003021-01-9

    Catalog No. EBD2185023

    CAS 1003021-01-9

    Name (R)-5-Amino-piperidin-2-one.HCl

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    Basic Information

    Synonyms: (5R)-5-氨基哌啶-2-一盐酸盐 (5R)-5-氨基哌啶-2-一盐酸盐 (5R)-5-氨基哌啶-2-酮盐酸盐 (R)-5-氨基-2-哌啶酮盐酸盐

    Molecular Formula: C5H11ClN2O

    Molecular Weight: 150.61

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (5R)-5-Aminopiperidin-2-one hydrochloride is a chiral piperidinone derivative, specifically the hydrochloride salt of the (R)-enantiomer. It features both a primary amine and a lactam (cyclic amide) functional group within a six-membered heterocyclic ring, making it a versatile and valuable chiral building block. This compound is primarily utilized as a key intermediate in pharmaceutical research and development. Its chiral, functionalized piperidine scaffold is a privileged structure found in numerous bioactive molecules. It serves as a crucial precursor for the synthesis of various drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas where the piperidine motif is prevalent. As a bifunctional chiral synthon, it is also employed in organic synthesis for constructing complex nitrogen-containing heterocycles. Its availability in enantiomerically pure form is essential for producing optically active final compounds, highlighting its importance in modern asymmetric synthesis and medicinal chemistry.
    Physical Properties
    mg g kg ml l t