3-Pyridinemethanol, CAS No. 100-55-0

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100-55-0

Catalog No. EBD1837862

CAS 100-55-0

Name 3-Pyridinemethanol

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Basic Information

Synonyms: 3-Pyridinemethanol 3-(Hydroxymethyl)pyridine Pyridine-3-methanol 3-Pyridylcarbinol Nicotinylalcohol Pyridine-3-carbinol pyridin-3-ylmethanol 3-Pyridinylmethanol beta-picolylalcohol beta-pyridinecarbinol beta-pyridylcarbinol niltuvin(freebase) nu-2121

Molecular Formula: C6H7NO

Molecular Weight: 109.13

MDL Number: MFCD00006407

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

3-(Hydroxymethyl)pyridine is an organic compound featuring a pyridine ring substituted with a hydroxymethyl group at the 3-position. It is a colorless to pale yellow liquid with a molecular formula of C6H7NO. This compound serves as a versatile and important heterocyclic building block in organic synthesis. Its primary industrial application is as a key pharmaceutical intermediate. It is notably used in the synthesis of various active pharmaceutical ingredients (APIs), including the anti-tuberculosis drug pyrazinamide and the anti-ulcer drug pirenzepine. The hydroxymethyl group provides a reactive handle for further chemical transformations, making it a valuable precursor in medicinal chemistry. Beyond its pharmaceutical applications, 3-(hydroxymethyl)pyridine is also employed as a ligand in coordination chemistry and as a starting material for the synthesis of other functionalized pyridine derivatives used in research and material science.

Physical Properties

Melting Point: -7 °C

Boiling Point: 154 °C/28 mmHg(lit.)

Flash Point: 110 °C

Density: 1.124 g/mL at 25 °C(lit.)

Solubility: soluble

Refractivity: n20/D 1.545(lit.)

Storage: 2-8°C

Analytical Data

Appearance: clear light yellow to yellow liquid